Epigenetics & Chromatin is affiliated with the International Society for Molecular and Clinical Epigenetics (isMOCLEP). isMOCLEP is open to all those interested in the wide spectrum of epigenetic research, from molecular to clinical aspects. isMOCLEP community welcomes academic researchers, early career scientists, companies, policy makers, and beyond.
TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation
Poly(ADP-ribosyl)ation (PARylation), a posttranslational modification introduced by PARP-1 and PARP-2, has first been implicated in DNA demethylation due to its role in base excision repair. Recent evidence in...