Epigenetics & Chromatin

Featured article: High-resolution mapping of centromeric protein association using APEX-chromatin fibers

The centromere is a specialized chromosomal locus that forms the basis for the assembly of a multi-protein complex, the kinetochore and ensures faithful chromosome segregation during every cell division. The repetitive nature of the underlying centromeric sequence represents a major obstacle for high-resolution mapping of protein binding using methods that rely on annotated genomes. Here, we present a novel microscopy-based approach called “APEX-chromatin fibers” for localizing protein binding over the repetitive centromeric sequences at kilobase resolution.

Editors-in-Chief

Frank Grosveld, Erasmus University Medical Center
Steven Henikoff, Fred Hutchinson Cancer Research Center

Content type: Research
| 15 February 2019

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

Authors: René A. M. Dirks, Guido van Mierlo, Hindrik H. D. Kerstens, Andreia S. Bernardo, Julianna Kobolák, István Bock, Julien Maruotti, Roger A. Pedersen, András Dinnyés, Martijn A. Huynen, Alice Jouneau and Hendrik Marks
Content type: Research
| 14 February 2019

Retinal-input-induced epigenetic dynamics in the developing mouse dorsal lateral geniculate nucleus

Authors: Jianlin He, Xiguang Xu, Aboozar Monavarfeshani, Sharmi Banerjee, Michael A. Fox and Hehuang Xie
Content type: Research
| 12 February 2019

Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups

Authors: Katherine A. Giles, Cathryn M. Gould, Qian Du, Ksenia Skvortsova, Jenny Z. Song, Madhavi P. Maddugoda, Joanna Achinger-Kawecka, Clare Stirzaker, Susan J. Clark and Phillippa C. Taberlay
Content type: Research
| 8 February 2019

Coordination between TGF-β cellular signaling and epigenetic regulation during epithelial to mesenchymal transition

Authors: Congcong Lu, Simone Sidoli, Katarzyna Kulej, Karen Ross, Cathy H. Wu and Benjamin A. Garcia
Content type: Research
| 1 February 2019

Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers

Authors: Charles E. Mordaunt, Dorothy A. Kieffer, Noreene M. Shibata, Anna Członkowska, Tomasz Litwin, Karl-Heinz Weiss, Yihui Zhu, Christopher L. Bowlus, Souvik Sarkar, Stewart Cooper, Yu-Jui Yvonne Wan, Mohamed R. Ali, Janine M. LaSalle and Valentina Medici

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Content type: Review
| 20 November 2014

Chromatin accessibility: a window into the genome

Authors: Maria Tsompana and Michael J Buck
Content type: Review
| 15 January 2015

Constitutive heterochromatin formation and transcription in mammals

Authors: Nehmé Saksouk, Elisabeth Simboeck and Jérôme Déjardin
Content type: Review
| 29 June 2016

Profiling genome-wide DNA methylation

Authors: Wai-Shin Yong, Fei-Man Hsu and Pao-Yang Chen
Content type: Review
| 2 April 2013

Mitotic bookmarking by transcription factors

Authors: Stephan Kadauke and Gerd A Blobel
Content type: Methodology
| 5 July 2013

A quantitative atlas of histone modification signatures from human cancer cells

Authors: Gary LeRoy, Peter A DiMaggio, Eric Y Chan, Barry M Zee, M Andres Blanco, Barbara Bryant, Ian Z Flaniken, Sherry Liu, Yibin Kang, Patrick Trojer and Benjamin A Garcia

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Aims and scope

Epigenetics & Chromatin is a peer-reviewed, open access journal that publishes research, and reviews, providing novel insights into epigenetic inheritance and chromatin-based interactions. The journal aims to understand how gene and chromosomal elements are regulated and their activities maintained during processes such as cell division, differentiation and environmental alteration.

Efficient peer review

Expedited: we recognise that scientifically sound, high quality manuscripts are often turned away from broad-scope "high-impact" journals based on the issue of "general interest." As a specialist journal, Epigenetics & Chromatin will consider rapid publication of such manuscripts if they are submitted as presubmission inquiries together with the original peer reviewer reports, letter of rejection, and a brief rebuttal.

Journal Authority Factor = 111.5

The Journal Authority Factor (JAF) is the average h-index of a journal’s senior editors. The JAF thus complements the Impact Factor by providing a measure of the experience of journal editors as practicing scientists and authors. All manuscripts submitted to Epigenetics & Chromatin are evaluated by the Editors-in-Chief, who also recommend reviewers, evaluate reviews and make all decisions regarding acceptance, revision or rejection. Our JAF of 111.5 compares favorably with that of academic society journals and professionally edited journals.

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Featured article: High-resolution mapping of centromeric protein association using APEX-chromatin fibers

Editors-in-Chief

Articles

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

Retinal-input-induced epigenetic dynamics in the developing mouse dorsal lateral geniculate nucleus

Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups

Coordination between TGF-β cellular signaling and epigenetic regulation during epithelial to mesenchymal transition

Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers

Chromatin accessibility: a window into the genome

Constitutive heterochromatin formation and transcription in mammals

Profiling genome-wide DNA methylation

Mitotic bookmarking by transcription factors

A quantitative atlas of histone modification signatures from human cancer cells

Aims and scope

Efficient peer review

Journal Authority Factor = 111.5

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Epigenetics & Chromatin

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