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Featured article: Same agent, different messages

SIN3 is a global transcriptional coregulator that governs expression of a large repertoire of gene targets. It is an important player in gene regulation, which can repress or activate diverse gene targets in a context-dependent manner. SIN3 is required for several vital biological processes such as cell proliferation, energy metabolism, organ development, and cellular senescence.  In this review, we discuss the differences in structure and function of distinct SIN3 isoforms and provide possible avenues to understand the complete picture of regulation by SIN3.

Editors-in-Chief

Frank Grosveld, Erasmus University Medical Center
Steven Henikoff, Fred Hutchinson Cancer Research Center

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Aims and scope

Epigenetics & Chromatin is a peer-reviewed, open access journal that publishes research, and reviews, providing novel insights into epigenetic inheritance and chromatin-based interactions. The journal aims to understand how gene and chromosomal elements are regulated and their activities maintained during processes such as cell division, differentiation and environmental alteration.

Efficient peer review

Rapid: our Editors-in-Chief maintain an average time from submission to a first decision of 21.5 days.

Expedited: we recognise that scientifically sound, high quality manuscripts are often turned away from broad-scope "high-impact" journals based on the issue of "general interest." As a specialist journal, Epigenetics & Chromatin will consider rapid publication of such manuscripts if they are submitted as presubmission inquiries together with the original peer reviewer reports, letter of rejection, and a brief rebuttal.

Journal Authority Factor = 111.5

The Journal Authority Factor (JAF) is the average h-index of a journal’s senior editors. The JAF thus complements the Impact Factor by providing a measure of the experience of journal editors as practicing scientists and authors. All manuscripts submitted to Epigenetics & Chromatin are evaluated by the Editors-in-Chief, who also recommend reviewers, evaluate reviews and make all decisions regarding acceptance, revision or rejection. Our JAF of 111.5 compares favorably with that of academic society journals, such as  PNAS  (59.9), and professionally edited journals, such as Nature (6.5). 

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