Epigenetics & Chromatin

Featured article: a critical role for SETDB1

The product of dosage compensation in female mammals is the inactive X chromosome (Xi). Xi facultative heterochromatin is organized into two different types, one of which is defined by histone H3 trimethylated at lysine 9 (H3K9me3). The rationale for this study was to assess SET domain bifurcated 1 (SETDB1) as a candidate for maintaining this repressive modification at the human Xi. The enzyme is shown to play a critical role.

Editors-in-Chief

Frank Grosveld, Erasmus University Medical Center
Steven Henikoff, Fred Hutchinson Cancer Research Center

Content type: Research
| 13 August 2018

Loss of SETDB1 decompacts the inactive X chromosome in part through reactivation of an enhancer in the IL1RAPL1 gene

Authors: Zhuo Sun and Brian P. Chadwick
Content type: Research
| 2 August 2018

EZH2 promotes DNA replication by stabilizing interaction of POLδ and PCNA via methylation-mediated PCNA trimerization

Authors: Peng A, Xinyi Xu, Chenglin Wang, Jing Yang, Shida Wang, Jiewen Dai and Ling Ye
Content type: Research
| 1 August 2018

CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

Authors: Philip A. Ruzycki, Xiaodong Zhang and Shiming Chen
Content type: Research
| 1 August 2018

Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements

Authors: Laxmi Narayan Mishra, Vasantha Shalini, Nikhil Gupta, Krittika Ghosh, Neeraj Suthar, Utsa Bhaduri and M. R. Satyanarayana Rao
Content type: Research
| 25 July 2018

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

Authors: Gilles Gasparoni, Sebastian Bultmann, Pavlo Lutsik, Theo F. J. Kraus, Sabrina Sordon, Julia Vlcek, Vanessa Dietinger, Martina Steinmaurer, Melanie Haider, Christopher B. Mulholland, Thomas Arzberger, Sigrun Roeber, Matthias Riemenschneider, Hans A. Kretzschmar, Armin Giese, Heinrich Leonhardt…

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Content type: Review
| 20 November 2014

Chromatin accessibility: a window into the genome

Authors: Maria Tsompana and Michael J Buck
Content type: Review
| 15 January 2015

Constitutive heterochromatin formation and transcription in mammals

Authors: Nehmé Saksouk, Elisabeth Simboeck and Jérôme Déjardin
Content type: Review
| 29 June 2016

Profiling genome-wide DNA methylation

Authors: Wai-Shin Yong, Fei-Man Hsu and Pao-Yang Chen
Content type: Review
| 2 April 2013

Mitotic bookmarking by transcription factors

Authors: Stephan Kadauke and Gerd A Blobel
Content type: Methodology
| 5 July 2013

A quantitative atlas of histone modification signatures from human cancer cells

Authors: Gary LeRoy, Peter A DiMaggio, Eric Y Chan, Barry M Zee, M Andres Blanco, Barbara Bryant, Ian Z Flaniken, Sherry Liu, Yibin Kang, Patrick Trojer and Benjamin A Garcia

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Aims and scope

Epigenetics & Chromatin is a peer-reviewed, open access journal that publishes research, and reviews, providing novel insights into epigenetic inheritance and chromatin-based interactions. The journal aims to understand how gene and chromosomal elements are regulated and their activities maintained during processes such as cell division, differentiation and environmental alteration.

Efficient peer review

Expedited: we recognise that scientifically sound, high quality manuscripts are often turned away from broad-scope "high-impact" journals based on the issue of "general interest." As a specialist journal, Epigenetics & Chromatin will consider rapid publication of such manuscripts if they are submitted as presubmission inquiries together with the original peer reviewer reports, letter of rejection, and a brief rebuttal.

Journal Authority Factor = 111.5

The Journal Authority Factor (JAF) is the average h-index of a journal’s senior editors. The JAF thus complements the Impact Factor by providing a measure of the experience of journal editors as practicing scientists and authors. All manuscripts submitted to Epigenetics & Chromatin are evaluated by the Editors-in-Chief, who also recommend reviewers, evaluate reviews and make all decisions regarding acceptance, revision or rejection. Our JAF of 111.5 compares favorably with that of academic society journals, such as PNAS (59.9), and professionally edited journals, such as Nature (6.5).

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Featured article: a critical role for SETDB1

Editors-in-Chief

Articles

Loss of SETDB1 decompacts the inactive X chromosome in part through reactivation of an enhancer in the IL1RAPL1 gene

EZH2 promotes DNA replication by stabilizing interaction of POLδ and PCNA via methylation-mediated PCNA trimerization

CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

Chromatin accessibility: a window into the genome

Constitutive heterochromatin formation and transcription in mammals

Profiling genome-wide DNA methylation

Mitotic bookmarking by transcription factors

A quantitative atlas of histone modification signatures from human cancer cells

Aims and scope

Efficient peer review

Journal Authority Factor = 111.5

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