Wei Y, Schatten H, Sun QY. Environmental epigenetic inheritance through gametes and implications for human reproduction. Hum Reprod Update. 2015;21(2):194–208.
Article
CAS
Google Scholar
Pembrey ME, Bygren LO, Kaati G, Edvinsson S, Northstone K, Sjöström M, Golding J. Sex-specific, male-line transgenerational responses in humans. Eur J Hum Genet EJHG. 2006;14(2):159–66.
Article
Google Scholar
Northstone K, Golding J, Davey Smith G, Miller LL, Pembrey M. Prepubertal start of father’s smoking and increased body fat in his sons: further characterisation of paternal transgenerational responses. Eur J Hum Genet EJHG. 2014;22(12):1382–6.
Article
Google Scholar
Mejia-Lancheros C, Mehegan J, Murrin CM, Kelleher CC. Smoking habit from the paternal line and grand-child’s overweight or obesity status in early childhood: prospective findings from the lifeways cross-generation cohort study. Int J Obes. 2018;42(11):1853–70.
Article
Google Scholar
Saleh RA, Agarwal A, Sharma RK, Nelson DR, Thomas AJ. Effect of cigarette smoking on levels of seminal oxidative stress in infertile men: a prospective study. Fertil Steril. 2002;78(3):491–9.
Article
Google Scholar
Wu Q, Ni X. ROS-mediated DNA methylation pattern alterations in carcinogenesis. Curr Drug Targets. 2015;16(1):13–9.
Article
Google Scholar
Sullivan EL, Grove KL. Metabolic imprinting in obesity. Forum Nutr. 2010;63:186–94.
Article
CAS
Google Scholar
Hur SSJ, Cropley JE, Suter CM. Paternal epigenetic programming: evolving metabolic disease risk. J Mol Endocrinol. 2017;58(3):R159–68.
Article
CAS
Google Scholar
Correra RM, Ollitrault D, Valente M, Mazzola A, Adalsteinsson BT, Ferguson-Smith AC, Marazzi G, Sassoon DA. The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal. Sci Rep. 2018;8(1):14649.
Article
Google Scholar
Laborda J, Sausville EA, Hoffman T, Notario V. Dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line. J Biol Chem. 1993;268(6):3817–20.
Article
CAS
Google Scholar
Gomes LG, Cunha-Silva M, Crespo RP, Ramos CO, Montenegro LR, Canton A, Lees M, Spoudeas H, Dauber A, Macedo DB, Bessa DS, Maciel GA, Baracat EC, Jorge AAL, Mendonca BB, Brito VN, Latronico AC. DLK1 is a novel link between reproduction and metabolism. J Clin Endocrinol Metab. 2019;104(6):2112–20.
Article
Google Scholar
Chacón MR, Miranda M, Jensen CH, Fernández-Real JM, Vilarrasa N, Gutiérrez C, Näf S, Gomez JM, Vendrell J. Human serum levels of fetal antigen 1 (FA1/Dlk1) increase with obesity, are negatively associated with insulin sensitivity and modulate inflammation in vitro. Int J Obes. 2008;32(7):1122–9.
Article
Google Scholar
Jensen CH, Kosmina R, Rydén M, Baun C, Hvidsten S, Andersen MS, Christensen LL, Gastaldelli A, Marraccini P, Arner P, Jørgensen CD, Laborda J, Holst JJ, Andersen DC. The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake. EBioMedicine. 2019;46:368–80.
Article
Google Scholar
Villena JA, Choi CS, Wang Y, Kim S, Hwang Y-J, Kim Y-B, Cline G, Shulman GI, Sul HS. Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy. Diabetes. 2008;57(12):3258–66.
Article
CAS
Google Scholar
Geuns E, De Temmerman N, Hilven P, Van Steirteghem A, Liebaers I, De Rycke M. Methylation analysis of the intergenic differentially methylated region of DLK1-GTL2 in human. Eur J Hum Genet EJHG. 2007;15(3):352–61.
Article
CAS
Google Scholar
Labialle S, Marty V, Bortolin-Cavaillé M-L, Hoareau-Osman M, Pradère J-P, Valet P, Martin PGP, Cavaillé J. The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014;33(19):2216–30.
Article
CAS
Google Scholar
Woodfine K, Huddleston JE, Murrell A. Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue. Epigenetics Chromatin. 2011;4(1):1.
Article
CAS
Google Scholar
Gagne A, Hochman A, Qureshi M, Tong C, Arbon J, McDaniel K, Davis TL. Analysis of DNA methylation acquisition at the imprinted Dlk1 locus reveals asymmetry at CpG dyads. Epigenetic Chromatin. 2014;7:9.
Article
Google Scholar
Yu B, Qi Y, Liu D, Gao X, Chen H, Bai C, Huang Z. Cigarette smoking is associated with abnormal histone-to-protamine transition in human sperm. Fertil Steril. 2013;101(1):51-57 e1.
Article
Google Scholar
Mai Z, Lei M, Yu B, Du H, Liu J. The effects of cigarette smoke extract on ovulation, oocyte morphology and ovarian gene expression in mice. PLoS ONE. 2014;9(4):e95945.
Article
Google Scholar
Wu X, Huang J, Dai L, Zhou J, Huang Z, Yu B. Adolescent diabetes induced by multiple parental exposures to cigarette smoke condensate. Toxicol Lett. 2019;314:98–105.
Article
CAS
Google Scholar
Olek A, Oswald J, Walter J. A modified and improved method for bisulphite based cytosine methylation analysis. Nucleic Acids Res. 1996;24(24):5064–6.
Article
CAS
Google Scholar
Lewin J, Schmitt AO, Adorján P, Hildmann T, Piepenbrock C. Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates. Bioinformatics. 2004;20(17):3005–12.
Article
CAS
Google Scholar
Guibert S, Forné T, Weber M. Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res. 2012;22(4):633–41.
Article
CAS
Google Scholar
Hammoud SS, Nix DA, Hammoud AO, Gibson M, Cairns BR, Carrell DT. Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men. Hum Reprod. 2011;26(9):2558–69.
Article
CAS
Google Scholar
Kiani J, Rassoulzadegan M. A load of small RNAs in the sperm—how many bits of hereditary information? Cell Res. 2013;23(1):18–9.
Article
CAS
Google Scholar
Uysal F, Akkoyunlu G, Ozturk S. DNA methyltransferases exhibit dynamic expression during spermatogenesis. Reprod Biomed Online. 2016;33(6):690–702.
Article
CAS
Google Scholar
Yu B, Zhou H, Liu M, Zheng T, Jiang L, Zhao M, Xu X, Huang Z. Epigenetic alterations in density selected human spermatozoa for assisted reproduction. PLoS ONE. 2015;10(12):e0145585.
Article
Google Scholar
Hamad MF, Dayyih WAA, Laqqan M, AlKhaled Y, Montenarh M, Hammadeh ME. The status of global DNA methylation in the spermatozoa of smokers and non-smokers. Reprod Biomed Online. 2018;37(5):581–9.
Article
CAS
Google Scholar
Jenkins TG, James ER, Alonso DF, Hoidal JR, Murphy PJ, Hotaling JM, Cairns BR, Carrell DT, Aston KI. Cigarette smoking significantly alters sperm DNA methylation patterns. Andrology. 2017;5(6):1089–99.
Article
CAS
Google Scholar
Liang F, Diao L, Liu J, Jiang N, Zhang J, Wang H, Zhou W, Huang G, Ma D. Paternal ethanol exposure and behavioral abnormities in offspring: associated alterations in imprinted gene methylation. Neuropharmacology. 2014;81:126–33.
Article
CAS
Google Scholar
Wei Y, Yang CR, Wei YP, Zhao ZA, Hou Y, Schatten H, Sun QY. Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals. Proc Natl Acad Sci USA. 2014;111(5):1873–8.
Article
CAS
Google Scholar
Takada S, Tevendale M, Baker J, Georgiades P, Campbell E, Freeman T, Johnson MH, Paulsen M, Ferguson-Smith AC. Delta-like and gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12. Curr Biol. 2000;10(18):1135–8.
Article
CAS
Google Scholar
Lin SP, Youngson N, Takada S, Seitz H, Reik W, Paulsen M, Cavaille J, Ferguson-Smith AC. Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet. 2003;35(1):97–102.
Article
CAS
Google Scholar
Jiang Y, Yu Y-C, Ding G-L, Gao Q, Chen F, Luo Q. Intrauterine hyperglycemia induces intergenerational Dlk1-Gtl2 methylation changes in mouse placenta. Oncotarget. 2018;9(32):22398–405.
Article
Google Scholar
Abdallah BM, Ditzel N, Laborda J, Karsenty G, Kassem M. DLK1 regulates whole-body glucose metabolism: a negative feedback regulation of the osteocalcin-insulin loop. Diabetes. 2015;64(9):3069–80.
Article
CAS
Google Scholar
Wurst U, Ebert T, Kralisch S, Stumvoll M, Fasshauer M. Serum levels of the adipokine Pref-1 in gestational diabetes mellitus. Cytokine. 2014;71(2):161–4.
Article
Google Scholar
Schneider G, Bowser MJ, Shin DM, Barr FG, Ratajczak MZ. The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas. Int J Oncol. 2013;44(1):295–300.
Article
Google Scholar