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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Effects of paternal exposure to cigarette smoke on sperm DNA methylation and long-term metabolic syndrome in offspring

Fig. 2

Methylation and Dlk1 expression levels in paternal sperm and the F1 generation of the mouse model. a Model of the CpG site in the IG-DMR at the Dlk1/Gtl2 locus in mouse. b Global DNA-methylation level (5-mC) in paternal sperm cells. c Expression level of Dlk1 in liver from 10-week-old F1 offspring. d Methylation levels of the IG-DMR in paternal sperm cells. e Methylation levels of IG-DMR in F2 liver cells. IG-DMR, intergenic differentially methylated region. M mean of 27 CpG sites. CON-M and CON-F male and female offspring of the CSE group; CSE-M and CSE-F male and female offspring of the CON group. *p  < 0.05.**p  < 0.01.***p  < 0.001 compared to the CON group

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Epigenetics & Chromatin

ISSN: 1756-8935