The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor

Table 3 DMCs and DMRs in Flv1-treated and control group for each generation

Generation	q value = 0.05, difference = 15% DMCs	q value = 1.0, difference = 4% DMCs	q value = 0.05, difference = 15% Hypomethylated DMCs	q value = 1.0, difference = 4% Hypomethylated DMCs	q value = 0.05, difference = 15% Hypermethylated DMCs	q value = 1.0, difference = 4% Hypermethylated DMCs
F0	44	245	31	153	13	92
F1	332	1900	207	1153	125	747
F0 and F1	6	41	6	23	0	18
Generation	q value = 0.05, difference = 15% DMRs	q value = 1, difference = 4% DMRs	q value = 0.0.5, difference = 15% Hypomethylated DMRs	q value = 0.1, difference = 4% Hypomethylated DMRs	q value = 0.0.5, difference = 15% Hypermethylated DMRs	q value = 0.1, difference = 4% Hypermethylated DMRs
F0	10	32	6	17	4	15
F1	51	345	38	200	13	145
F0 and F1	1	7	1	5	0	2

Two setting parameters were used to calculate the DMCs, the strict parameters with a q value < 0.05 and a cutoff of 15% methylation difference and the adapted parameters with a q value < 1 and a cutoff of 4%

ISSN: 1756-8935