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Table 7 Results from a two-way ANCOVA for mRNA expression in ventricles from juvenile snapping turtles

From: Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

Gene Oxygen treatment Age Oxygen treatment × age Covariate
CALR F1,20 = 0.27, p = 0.61 F1,20 = 4.5, p = 0.05 F1,20 = 0.18, p = 0.68 F1,20 = 0.71, p = 0.41
COL8A1 F1,20 = 6.9, p = 0.02 F1,20 = 15.5, p = 0.0008 F1,20 = 3.6, p = 0.07 F1,20 = 8.3, p = 0.009
DDIT4L F1,20 = 9.3, p = 0.006 F1,20 = 0.21, p = 0.65 F1,20 = 0.20, p = 0.66 F1,20 = 14.4, p = 0.001
HIF1A F1,20 = 3.85, p = 0.06 F1,20 = 0.04, p = 0.85 F1,20 = 6.0, p = 0.02 F1,20 = 0.96, p = 0.34
HTRA3 F1,19 = 5.2, p = 0.03 F1,19 = 3.9, p = 0.06 F1,19 = 6.2, p = 0.02 F1,19 = 6.0, p = 0.02
ITGA11 F1,20 = 5.4, p = 0.03 F1,20 = 4.4, p = 0.05 F1,20 = 0.66, p = 0.43 F1,20 = 0.95, p = 0.34
MIPEP F1,20 = 8.2, p = 0.01 F1,20 = 0.14, p = 0.71 F1,20 = 0.04, p = 0.85 F1,20 = 8.9, p = 0.007
MNAT1 F1,20 = 9.2, p = 0.006 F1,20 = 3.1, p = 0.09 F1,20 = 0.48, p = 0.5 F1,20 = 0.08, p = 0.78
NCOA2 F1,20 = 5.9, p = 0.02 F1,20 = 5.1, p = 0.03 F1,20 = 2.26, p = 0.15 F1,20 = 7.9, p = 0.01
PFKFB1 F1,20 = 20.8, p = 0.0002 F1,20 = 10.4, p = 0.004 F1,20 = 15.4, p = 0.0008 F1,20 = 2.2, p = 0.15
PPIA F1,20 = 5.3, p = 0.03 F1,20 = 3.3, p = 0.08 F1,20 = 0.24, p = 0.63 F1,20 = 0.17, p = 0.69
SCN5A F1,17 = 4.6, p = 0.05 F1,17 = 0.04, p = 0.85 F1,17 = 7.3, p = 0.015 F1,17 = 16.5, p = 0.0008
SNTB1 F1,20 = 0.05, p = 0.82 F1,20 = 4.3, p = 0.05 F1,20 = 0.79, p = 0.38 F1,20 = 0.003, p = 0.96
TNNT2 F1,20 = 6.0, p = 0.02 F1,20 = 0.01, p = 0.93 F1,20 = 0.13, p = 0.72 F1,20 = 0.12, p = 0.74
TPM3 F1,20 = 12.5, p = 0.002 F1,20 = 1.6, p = 0.22 F1,20 = 0.32, p = 0.58 F1,20 = 1.8, p = 0.19
WNT11 F1,20 = 4.6, p = 0.04 F1,20 = 3.4, p = 0.08 F1,20 = 0.01, p = 0.92 F1,20 = 1.3, p = 0.27
  1. Oxygen treatment, age, and the oxygen treatment by age interaction were fixed effects in the model. The first principal component from a principal components analysis of CACNA2D1, CNP, and YTHDF3 expression was used as the covariate in the ANCOVA. Significant effects (p ≤ 0.05) are highlighted in bolditalics
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Epigenetics & Chromatin

ISSN: 1756-8935