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Table 5 GO biological process terms and genes that were enriched among differentially expressed genes in ventricles from juvenile snapping turtles

From: Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

locus_number (in snapping turtle)

gene_name

gene_symbol

Sarcomere organization

 CS000009788

Bone morphogenetic protein 10

BMP10

 CS000018274

Cysteine and glycine rich protein 1

CSRP1

 CS000002632

Cysteine and glycine rich protein 3

CSRP3

 CS000023885

Formin homology 2 domain containing 3

FHOD3

 CS000019220

Keratin 8

KRT8

 CS000005252

Myomesin 3

MYOM3

 CS000000499

Myopalladin

MYPN

 CS000000944

Troponin T2, cardiac type

TNNT2

Cell adhesion = biological adhesion

 CS000007175

Adhesion G protein-coupled receptor L3

ADGRL3

 CS000009633

Activated leukocyte cell adhesion molecule

ALCAM

 CS000004780

Amyloid beta precursor protein-binding family A member 1

APBA1

 CS000009788

Bone morphogenetic protein 10

BMP10

 CS000003073

Cadherin 11, type 2, OB-cadherin (osteoblast)

CDH11

 CS000003093

Cadherin 13

CDH13

 CS000014745

Cadherin EGF LAG seven-pass G-type receptor 3

celsr3

 CS000008605

Contactin associated protein 1

CNTNAP1

 CS000002886

Collagen type XV alpha 1 chain

COL15A1

 CS000014058

Collagen, type XVIII, alpha 1

COL18A1

 CS000004853

Collagen type III alpha 1 chain

COL3A1

 CS000025399

Collagen type IV alpha 6 chain

COL4A6

 CS000009656

Collagen type VIII alpha 1 chain

COL8A1

 CS000018274

Cysteine and glycine rich protein 1

CSRP1

 CS000007341

Catenin delta 1

CTNND1

 CS000021606

Ependymin related 1

EPDR1

 CS000003405

Fibronectin 1

FN1

 CS000001877

Glycoprotein nmb

GPNMB

 CS000018642

Hyaluronan-binding protein 2

HABP2

 CS000007378

Heat shock protein family B (small) member 1

HSPB1

 CS000012953

Immunoglobulin superfamily containing leucine-rich repeat

ISLR

 CS000008411

Integrin subunit alpha 11

ITGA11

 CS000009567

Keratin 18

KRT18

 CS000017005

Muskelin 1

MKLN1

 CS000020271

Myosin, light chain 12A, regulatory, non-sarcomeric

MYL12A

 CS000000499

myopalladin

MYPN

 CS000008885

Neural precursor cell expressed, developmentally down-regulated 9

NEDD9

 CS000018597

Neurexin 2

NRXN2

 CS000002394

Neurotrimin

NTM

 CS000019311

Protein kinase C alpha

PRKCA

 CS000011090

Secreted phosphoprotein 1

SPP1

 CS000020166

Tweety family member 1

TTYH1

 CS000020993

TYRO3 protein tyrosine kinase

TYRO3

Signal transduction

 CS000017075

Adhesion G protein-coupled receptor D2

ADGRD2

 CS000009646

Adhesion G protein-coupled receptor G7

ADGRG7

 CS000007175

Adhesion G protein-coupled receptor L3

ADGRL3

 CS000003393

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

AGAP1

 CS000009633

Activated leukocyte cell adhesion molecule

ALCAM

 CS000011198

Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

APPL1

 CS000002385

Rho GTPase-activating protein 32

ARHGAP32

 CS000021833

Rho GTPase activating protein 45

ARHGAP45

 CS000023302

Cdc42 guanine nucleotide exchange factor 9

ARHGEF9

 CS000003395

Ankyrin repeat and SOCS box containing 18

ASB18

 CS000001723

ATM serine/threonine kinase

ATM

 CS000013883

BCL tumor suppressor 7B

BCL7B

 CS000009788

Bone morphogenetic protein 10

BMP10

 CS000004917

Bone morphogenetic protein receptor type 2

BMPR2

 CS000014425

B-Raf proto-oncogene, serine/threonine kinase

BRAF

 CS000009112

Calcium-binding protein 5

CABP5

 CS000023033

Calcitonin receptor

CALCR

 CS000004923

CD28 molecule

CD28

 CS000003093

Cadherin 13

CDH13

 CS000014745

Cadherin EGF LAG seven-pass G-type receptor 3

celsr3

 CS000006114

chordin like 1

CHRDL1

 CS000008605

Contactin associated protein 1

CNTNAP1

 CS000002886

Collagen type XV alpha 1 chain

COL15A1

 CS000004853

Collagen type III alpha 1 chain

COL3A1

 CS000025399

Collagen type IV alpha 6 chain

COL4A6

 CS000009979

Cysteine rich transmembrane BMP regulator 1

CRIM1

 CS000011960

Crystallin alpha B

CRYAB

 CS000002632

Cysteine and glycine rich protein 3

CSRP3

 CS000007341

Catenin delta 1

CTNND1

 CS000003128

Cytochrome b-245 alpha chain

CYBA

 CS000005867

Epidermal growth factor receptor pathway substrate 8

EPS8

 CS000008545

Erb-b2 receptor tyrosine kinase 2

ERBB2

 CS000012011

Coagulation factor III, tissue factor

F3

 CS000002168

Fibroblast growth factor receptor 3

FGFR3

 CS000003405

Fibronectin 1

FN1

 CS000002902

Gamma-aminobutyric acid type B receptor subunit 1

GABBR1

 CS000008168

Glucagon

GCG

 CS000005687

G protein subunit alpha 12

GNA12

 CS000013318

G protein subunit gamma 10

GNG10

 CS000001877

Glycoprotein nmb

GPNMB

 CS000017383

G protein-coupled receptor 62

GPR62

 CS000008476

Growth factor receptor bound protein 10

GRB10

 CS000008544

Growth factor receptor bound protein 7

GRB7

 CS000006655

G protein-coupled receptor kinase 3

GRK3

 CS000020555

Granzyme H

GZMH

 CS000023516

Hypoxia inducible factor 1 alpha subunit

HIF1A

 CS000007378

Heat shock protein family B (small) member 1

HSPB1

 CS000000714

Interleukin 22

IL22

 CS000008411

Integrin subunit alpha 11

ITGA11

 CS000005400

Inositol-trisphosphate 3-kinase A

ITPKA

 CS000009858

Arginine demethylase and lysine hydroxylase

JMJD6

 CS000020495

Kinase non-catalytic C-lobe domain containing 1

KNDC1

 CS000009567

Keratin 18

KRT18

 CS000019220

Keratin 8

KRT8

 CS000015494

Limb development membrane protein 1

LMBR1

 CS000008774

Mitogen-activated protein kinase kinase kinase 5

MAP3K5

 CS000003679

Mitogen-activated protein kinase 9

MAPK9

 CS000001243

Myelin basic protein

MBP

 CS000023152

Mindbomb E3 ubiquitin protein ligase 1

MIB1

 CS000017005

Muskelin 1

MKLN1

 CS000014226

MOB kinase activator 1B

MOB1B

 CS000012971

Neuron derived neurotrophic factor

NDNF

 CS000008885

Neural precursor cell expressed, developmentally down-regulated 9

NEDD9

 CS000001770

Neuroepithelial cell transforming 1

NET1

 CS000000790

NFKB inhibitor like 1

NFKBIL1

 CS000018597

Neurexin 2

NRXN2

 CS000014447

PDZ-binding kinase

PBK

 CS000003989

Pleckstrin homology domain interacting protein

PHIP

 CS000000947

Pleckstrin homology-like domain family A member 3

PHLDA3

 CS000010015

Proteolipid protein 1

PLP1

 CS000000163

DNA polymerase kappa

POLK

 CS000025418

Peptidylprolyl isomerase A

PPIA

 CS000008337

Protein phosphatase, Mg2+/Mn2+-dependent 1L

PPM1L

 CS000000189

Protein kinase AMP-activated non-catalytic subunit beta 2

PRKAB2

 CS000019311

Protein kinase C alpha

PRKCA

 CS000012528

Persephin

PSPN

 CS000009267

RAB32, member RAS oncogene family

RAB32

 CS000004444

RAB33A, member RAS oncogene family

RAB33A

 CS000007756

Raf-1 proto-oncogene, serine/threonine kinase

RAF1

 CS000001871

Rap guanine nucleotide exchange factor 5

RAPGEF5

 CS000015645

Regulator of cell cycle

RGCC

 CS000020112

Ral guanine nucleotide dissociation stimulator-like 2

RGL2

 CS000023359

Ral guanine nucleotide dissociation stimulator like 3

RGL3

 CS000008982

Regulator of G-protein signaling 5

RGS5

 CS000009817

Rho related BTB domain containing 2

RHOBTB2

 CS000011866

Ras homolog family member C

RHOC

 CS000000565

Ras and Rab interactor-like protein

RINL

 CS000012325

Receptor interacting serine/threonine kinase 2

RIPK2

 CS000012890

Sestrin 3

SESN3

 CS000021605

Secreted frizzled related protein 4

SFRP4

 CS000018595

Signal-induced proliferation-associated 1

SIPA1

 CS000005505

SIVA1 apoptosis inducing factor

SIVA1

 CS000012858

Suppressor of cytokine signaling 2

SOCS2

 CS000023280

Sorbin and SH3 domain containing 2

SORBS2

 CS000006802

Sortilin related VPS10 domain containing receptor 1

SORCS1

 CS000020596

Sortilin related VPS10 domain containing receptor 2

SORCS2

 CS000011090

Secreted phosphoprotein 1

SPP1

 CS000021122

Sprouty related EVH1 domain containing 2

SPRED2

 CS000003610

Serine/threonine kinase 32A

STK32A

 CS000024894

Serine/threonine kinase 38 like

STK38L

 CS000024997

Toll like receptor 6

TLR6

 CS000015148

Tumor necrosis factor superfamily member 10

TNFSF10

 CS000011024

Target of myb1 like 1 membrane trafficking protein

TOM1L1

 CS000019856

TNF receptor associated factor 2

TRAF2

 CS000012224

TNF receptor associated factor 3

TRAF3

 CS000018042

Tribbles pseudokinase 1

TRIB1

 CS000002912

Tripartite motif containing 21

TRIM21

 CS000005987

Tyrosine kinase 2

TYK2

 CS000020993

TYRO3 protein tyrosine kinase

TYRO3

 CS000017504

unc-5 netrin receptor A

UNC5A

 CS000002566

VAMP associated protein B and C

VAPB

 CS000025210

Wnt family member 11

WNT11

 CS000014907

Zinc finger protein 219

ZNF219

 CS000002650

Doublecortin domain containing 1

 

 CS000013923

Uncharacterized

 

 CS000014046

G protein-coupled receptor kinase 5-like

 

 CS000019987

Plexin A3

 

 CS000025011

Retinoic acid receptor, alpha

 
  1. Gene names and gene symbols are listed for each enriched GO term. Genes in the biological adhesion and cell adhesion lists were identical, because these are parent and child terms. GO terms were considered significant when FDR corrected p ≤ 0.05