Fig. 3

Annotation of significant peaks. a Example illustration of annotating significant differential peaks to enhancer, promoter, intragenic or intergenic regions. b Number of peaks per annotated category, separated by time. c All intergenic peaks plotted based on their proximity to the TSS of the closest gene. All enhancers were identified from within these regions and are coloured green. d Frequency distribution of significant peaks and proximity to the TSS of their associated genes (± 5 KB)