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Table 1 The known BRM interactors and processes involving BRM

From: BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?

Lp. Full name Abbreviations Gene name(s) Function; biological process Refs.
Transcription factors
 1 Androgen receptor AR AR, DHTR, NR3C4 Transcription regulation, hormone receptor [137,138,139]
 2 Breast cancer type 1 susceptibility protein; breast cancer 1, early onset BRCA1 BRCA1, RNF53 DNA repair, transcription regulation, metabolism [140,141,142]
 3 CCAAT/enhancer-binding protein alpha C/EBP alpha, CEBPA CEBPA, CEBP Transcription regulation, DNA-binding [143]
 4 Chromobox protein homolog 5 CBX5, HP1 alpha CBX5, HP1A Transcription regulation, chromatin organisation [144, 145]
 5 Endothelial PAS domain-containing protein 1 EPAS-1, bHLHe73, HLF, HIF-2-alpha EPAS1, BHLHE73, HIF2A, MOP2, PASD2 Transcription factor, hypoxia induced regulator of oxygen related genes [146]
 6 EP300-interacting inhibitor of differentiation 1 EP300, EID-1 EID1 C15orf3, CRI1, RBP21, PNAS-22, PTD014 Transcription regulation, cell cycle, differentiation [147]
 7 Oestrogen receptor ER ESR1, ESR, NR3A1 Transcription regulation, hormone receptor [148]
 8 Histone H2A deubiquitinase MYSM1 2A-DUB, MYSM1 MYSM1, KIAA1915 Transcription regulation, chromatin regulator [149]
 9 Histone deacetylase 1 HD1, HDAC1 HDAC1, RPD3L1 Histone deacetylase, transcription regulation [22, 150]
 10 Histone deacetylase 2 HD2, HDAC2 HDAC2 Histone deacetylase, transcription regulation [22, 150]
 11 Histone-lysine N-methyltransferase EZH2 EXH2, ENX-1 EZH2, KMT6 PRC2 main subunit, transcription regulation, chromatin regulation [151]
 12 Homeobox protein CDX-2 CDX-2 CDX2, CDX3 Transcription regulation, developmental protein [152]
 13 Hypoxia-inducible factor 1-alpha HIF-1-alpha, bHLHe78 HIF1A, BHLHE78, MOP1, PASD8 Transcription factor, master regulator of the adaptive response to hypoxia [153]
 14 Myc proto-oncogene protein c-Myc, bHLHe39 MYC, BHLHE39 Transcription factor recognising sequence 5′-CAC[GA]TG-3′ [154]
 15 Nuclear receptor corepressor 1 NCOR1 NCOR1, KIAA1047 Transcription regulation [155]
 16 Paired amphipathic helix protein Sin3a SIN3A SIN3A Transcription regulation [22, 150, 156]
 17 Polycomb protein EED EED, hEED, WAIT-1 WAIT-1 Transcription regulation, chromatin regulation [157]
 18 Signal transducer and activator of transcription 1-alpha/beta STAT1 Transcription factor [147]
 19 Transcription activator MYB c-Myb MYB Transcription regulation [158]
 20 Transcription factor AP-1 c-Jun, AP1, p39 JUN Transcription regulation [159]
 21 Transcription factor SOX-2 SOX2 SOX2 Transcription regulation [160, 161]
 22 Transcription initiation factor TFIID subunit 1 p250, TAF(II)250, TAFII-250, TAFII250 TAF1 Transcription regulation, cell cycle [150]
 23 DNA-directed RNA polymerase II subunit RPB1 POLR2A, RNAPII RNAPII, POLR2 RNA polymerase, transcription [53, 162]
 24 Protein arginine N-methyltransferase 5 PRMT5, SKB1 homolog, SKB1Hs PRMT5, HRMT1L5, IBP72, JBP1, SKB1 Arginine methyltransferase [156]
 25 Proto-oncogene c-Fos c-Fos FOS, G0S7 DNA-binding [159]