Table 1 The known BRM interactors and processes involving BRM

Transcription factors

 1

Androgen receptor

AR

AR, DHTR, NR3C4

Transcription regulation, hormone receptor

[137,138,139]

 2

Breast cancer type 1 susceptibility protein; breast cancer 1, early onset

BRCA1

BRCA1, RNF53

DNA repair, transcription regulation, metabolism

[140,141,142]

 3

CCAAT/enhancer-binding protein alpha

C/EBP alpha, CEBPA

CEBPA, CEBP

Transcription regulation, DNA-binding

[143]

 4

Chromobox protein homolog 5

CBX5, HP1 alpha

CBX5, HP1A

Transcription regulation, chromatin organisation

[144, 145]

 5

Endothelial PAS domain-containing protein 1

EPAS-1, bHLHe73, HLF, HIF-2-alpha

EPAS1, BHLHE73, HIF2A, MOP2, PASD2

Transcription factor, hypoxia induced regulator of oxygen related genes

[146]

 6

EP300-interacting inhibitor of differentiation 1

EP300, EID-1

EID1 C15orf3, CRI1, RBP21, PNAS-22, PTD014

Transcription regulation, cell cycle, differentiation

[147]

 7

Oestrogen receptor

ER

ESR1, ESR, NR3A1

Transcription regulation, hormone receptor

[148]

 8

Histone H2A deubiquitinase MYSM1

2A-DUB, MYSM1

MYSM1, KIAA1915

Transcription regulation, chromatin regulator

[149]

 9

Histone deacetylase 1

HD1, HDAC1

HDAC1, RPD3L1

Histone deacetylase, transcription regulation

[22, 150]

 10

Histone deacetylase 2

HD2, HDAC2

HDAC2

Histone deacetylase, transcription regulation

[22, 150]

 11

Histone-lysine N-methyltransferase EZH2

EXH2, ENX-1

EZH2, KMT6

PRC2 main subunit, transcription regulation, chromatin regulation

[151]

 12

Homeobox protein CDX-2

CDX-2

CDX2, CDX3

Transcription regulation, developmental protein

[152]

 13

Hypoxia-inducible factor 1-alpha

HIF-1-alpha, bHLHe78

HIF1A, BHLHE78, MOP1, PASD8

Transcription factor, master regulator of the adaptive response to hypoxia

[153]

 14

Myc proto-oncogene protein

c-Myc, bHLHe39

MYC, BHLHE39

Transcription factor recognising sequence 5′-CAC[GA]TG-3′

[154]

 15

Nuclear receptor corepressor 1

NCOR1

NCOR1, KIAA1047

Transcription regulation

[155]

 16

Paired amphipathic helix protein Sin3a

SIN3A

SIN3A

Transcription regulation

[22, 150, 156]

 17

Polycomb protein EED

EED, hEED, WAIT-1

WAIT-1

Transcription regulation, chromatin regulation

[157]

 18

Signal transducer and activator of transcription 1-alpha/beta

–

STAT1

Transcription factor

[147]

 19

Transcription activator MYB

c-Myb

MYB

Transcription regulation

[158]

 20

Transcription factor AP-1

c-Jun, AP1, p39

JUN

Transcription regulation

[159]

 21

Transcription factor SOX-2

SOX2

SOX2

Transcription regulation

[160, 161]

 22

Transcription initiation factor TFIID subunit 1

p250, TAF(II)250, TAFII-250, TAFII250

TAF1

Transcription regulation, cell cycle

[150]

Others

 23

DNA-directed RNA polymerase II subunit RPB1

POLR2A, RNAPII

RNAPII, POLR2

RNA polymerase, transcription

[53, 162]

 24

Protein arginine N-methyltransferase 5

PRMT5, SKB1 homolog, SKB1Hs

PRMT5, HRMT1L5, IBP72, JBP1, SKB1

Arginine methyltransferase

[156]

 25

Proto-oncogene c-Fos

c-Fos

FOS, G0S7

DNA-binding

[159]