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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

Fig. 3

ATAC-Seq profiles of hematopoietic populations. a Unsupervised hierarchical clustering analysis of ATAC-Seq-derived peak profiles. b Principle component analysis plotting PC1 versus. c ATAC-Seq peaks in LSK and maintained throughout erythro-megakaryopoiesis. Circle size is proportional to the percentage of peaks maintained from the LSK, dotted circle is proportional to the percentage of all peaks in the cell relative to the number maintained from LSK, and line length is inversely proportional to percentage of peaks maintained from the progenitor. The number and percentage of maintained LSK peaks is shown. d Proportional Venn diagram indicating overlap of ATAC-Seq peaks between CMP, ERY, and iMK populations

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Epigenetics & Chromatin

ISSN: 1756-8935