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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

Fig. 2

Transcriptional profiles of hematopoietic populations. a Unsupervised hierarchical clustering analysis of RNA-Seq-derived transcriptomes. b Principle component analysis plotting PC1 versus PC2. c Expressed transcripts in LSK and maintained throughout erythro-megakaryopoiesis. Solid circle size is proportional to the percentage of expressed transcripts maintained from the LSK, dotted circle is proportional to the percentage of all transcripts in the cell relative to the number maintained from LSK, and line length is inversely proportional to percentage of expressed transcripts maintained from the progenitor. The number and percentage of maintained LSK transcripts is shown. d Proportional Venn diagram indicating overlap of expressed genes between CMP, ERY, and iMK populations

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Epigenetics & Chromatin

ISSN: 1756-8935