Fig. 4
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13072-017-0142-4/MediaObjects/13072_2017_142_Fig4_HTML.gif)
High-resolution C-TALE-identified TAD profile around AgGD. a A schematic representation of the C-TALE procedure. For the experimental details, see “Methods” and Additional file 8: Supplementary Methods. b Heatmaps showing C-TALE data normalized by the total number of sequencing reads in the C-TALE dataset, binned at a 5 Kb resolution and iteratively corrected. Dashed lines show the positions of chromatin contact domain boundaries identified using the Lavaburst package. Gray triangles in the left panel represent 5C-identified TADs in DT40 cell line. Gene positions are shown on the diagonal of each panel, and a detailed map of the studied region is presented below the heatmaps. Dark triangles inside the gene boxes show the direction of transcription