Fig. 5

Analysis of heavily labeled methylations at days 1 and 2 of EMT. a Relative abundance of heavy labeled methylations, sorted by cumulative intensity for the days 1 and 2. In the smaller bar plot, zoom for the hybrid methylations, i.e., methylated states containing both unlabeled and heavy labeled methyl groups.Ring graph representing b positive and c negative interplay scores between methylations on K9, K27 and K36 sites. Line thickness represents interplay absolute values. High interplay values indicate that the two marks coexist on the same histone tail with a frequency higher (if positive) or lower (if negative) than random co-occurrence. d Most intense absolute interplay scores that include at least one hybrid mark