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Figure 6 | Epigenetics & Chromatin

Figure 6

From: Menin and RNF20 recruitment is associated with dynamic histone modifications that regulate signal transducer and activator of transcription 1 (STAT1)-activated transcription of the interferon regulatory factor 1 gene (IRF1)

Figure 6

RNF20 and MEN1 are constitutively associated with the interferon regulatory factor 1 gene ( IRF1 ) and recruited by interferon (IFN)γ induction. 2fTGH cells were induced with IFNγ for 30 min or uninduced. Chromatin immunoprecipitation (ChIP) was performed using antibodies against RNF20 (a) and MEN1 (b) and quantitative PCR (Q-PCR) quantified the precipitate yield, reported as percentage of input. MEN1 was not detectable using primer pairs beyond 3,000 bp.

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Epigenetics & Chromatin

ISSN: 1756-8935