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Table 3 Integration of RRBS data with RNA-Seq reveals genes that may be regulated by altered DNA methylation in response to different housing temperatures

From: Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress

Gene name

SC vs TN

RT vs TN

DMPs

DEGs

DMPs

DEGs

Meth Diff

Padj

Fold Change

Padj

Meth Diff

Padj

Fold Change

Padj

Tspan31

− 36.93

1.53E−47

1.20

1.06E−02

    

Dnajc14

− 34.23

1.67E−28

1.28

1.83E−06

    

Car13

− 31.99

8.74E−42

2.25

7.28E−19

− 30.66

4.79E−38

1.53

1.24E−07

Gm33699

− 25.58

4.08E−34

6.57

2.73E−13

    

Lyplal1

− 16.43

9.92E−10

2.65

2.59E−28

− 19.18

4.58E−17

1.78

1.43E−06

Uba1

− 15.99

4.05E−23

1.25

7.21E−04

    

Dlg3

− 11.02

1.55E−29

1.29

8.61E−03

    

Vma21

− 6.75

4.50E−14

1.80

1.48E−14

− 6.03

1.68E−11

1.53

2.66E−08

Vldlr

− 6.28

2.40E−08

1.38

5.22E−03

− 6.86

9.66E−14

1.78

1.06E−06

Ndufb11

− 5.19

1.47E−17

1.15

3.60E−02

− 5.39

3.89E−23

1.62

3.75E−08

Car8

    

− 5.28

3.30E−03

1.60

7.67E−04

Tpcn2

    

14.30

8.34E−05

0.54

2.90E−03

  1. n = 4 per group for each dataset. Meth Diff: differential methylation level. DMPs: differentially methylated promoters. DEGs: differentially expressed genes. TN: thermoneutral. RT: room temperature. SC: severe cold