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Fig. 14 | Epigenetics & Chromatin

Fig. 14

From: Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clusters

Fig. 14

An overview schematic of the indicated architectures of the different modified chromatin along the Y loops. There are a few potential topological structures of H3K4me3, the options are shown within the boxed area. From left to right, H3K4me3 may appear as a looping region on the periphery of a H3K27me3 cluster [1], H3K4me3 may appear as a connecting region in between H3K27me3 clusters [2] or in between histone labelled clusters [3], or potentially as small clusters along a chromatin fibre [4]. All of the structures indicated in this schematic are hypothetical based on the data presented in this work

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Epigenetics & Chromatin

ISSN: 1756-8935