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Fig. 12 | Epigenetics & Chromatin

Fig. 12

From: Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clusters

Fig. 12

Quantification of the average overall distance between RPol-Pser2 and H3K36me3, or H3K27me3. (A) individual ROIs containing the histone modifications and RPol-Pser2 along sections of the Y loop are plotted as individual lines using the empirical distribution function (ECDF); H3K36me3 in cyan, H3K27me3 in magenta. (B) the ECDF values at 90% were pooled for both H3K27me3 and H3K36me3 and plotted on a box and whiskers plot showing that H3K36me3 was closer on average to RPol-Pser2 signal. (C) the mark connection function was used as an alternative method in a more unbiased fashion, and also showed that RPol-Pser2 is closer to H3K36me3.

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Epigenetics & Chromatin

ISSN: 1756-8935