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Fig. 7 | Epigenetics & Chromatin

Fig. 7

From: Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers

Fig. 7

Gene Ontology (GO) analysis of Hi-C promoter chromatin contacts. GO analysis of chromatin loop contacts at or near promoters (2 kb upstream and 0.1 kb downstream of transcriptional start sites). (a) GO analysis of promoter contacts in ES cells. Note enriched terms related to embryonic development and cell fate commitment. (b) GO analysis of promoter contacts in lens epithelium. Note enriched terms related to epithelial morphogenesis, differentiation and proliferation. (c) GO analysis of promoter contacts in lens fiber cell promoter contacts. Note enriched terms related to development of the visual system. (d) Lens epithelium and fiber cells share more promoter contacts (n = 331) than with ES cells (n = 227 and n = 235, respectively). ES cells had the highest number of unique promoter contacts (n = 485) when compared with lens epithelium (n = 274) and lens fiber cells (n = 225)

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Epigenetics & Chromatin

ISSN: 1756-8935