Fig. 7

Global distribution of H3K27me3 and H3K4me3 and their role in gene transcription in TetOff::FfH2A.Z. (A) Global view on F. fujikuroi (FfWT) and TetOff::FfH2A.Z chromosomes I, IV, and XI and respective distribution of H3K4me3 and H3K27me3. Chromosomes I, IV, and XI are shown in dark gray, while centromeres are depicted in light gray. Genome-wide distribution of H3K4me3 is shown in green for FfWT and in light green for the FfH2A.Z knock-down strain. The global view of H3K27me3 in FfWT is depicted in red, while the mutant strain is shown in light red. CPM; counts per million reads, bp; base pair. (B) Visualization of FfH2A.Z-enriched and differentially transcribed genes (TetOff::FfH2A.Z – FfWT). In the left panel, differentially transcribed genes are shown in gray, while light-green markings indicate the presence of H3K4me3. The right panel represents FfH2A.Z-enriched genes (gray) and their differential transcription compared to FfWT. Genes decorated with facultative heterochromatin are marked in light red. (C) Depiction of remaining non-FfH2A.Z genes in regard to differential transcription. Differently transcribed genes are shown in gray (left and right panel), while H3K4me3-decorated genes are depicted in light green, and H3K27me3-enriched genes are shown in light red. The dashed lines determine the confidence interval of ≥ ± 1