Table 3 Naturally available compounds inhibiting the JAK/STAT pathway
From: Role of sex in immune response and epigenetic mechanisms
Compound name | Class | Natural sources | Mechanism of action | References |
|---|---|---|---|---|
Duramycin | Thiopeptide | Streptomycetes | CXCR 3 inhibitor | [61] |
Roselipins | Polyketide glycosides | Clonostachys rosea | CXCR 3 inhibitor | [61] |
Hypoglausin A | steroidal glycosides | Blighia sapida (ackee fruit) | CXCR 3 inhibitor | [61] |
Dioscin | Steroidal glycosides | Scrophularia nodosa L. (figwort) | CXCR 3 inhibitor | [61] |
Gallic acid | Phenolic acid | Blueberry, blackberry, strawberry, plums, grapes, mango, cashew nut, hazelnut, walnut, tea, wine | IL2 inhibitor, FoxP3 inhibitor | [38] |