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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease

Fig. 2

Identification of TADs, Loops and Chromatin Compartments using Hi–C data produced with different enzymes. A Quantification of the compartment strength using saddle plots. Left plot shows how preference of homotypic interactions (i.e., interactions within the same compartment) of the locus scales with its compartment attribution score. Right panel shows the same data in the form of a single score computed as area under the curve. B Aggregate TAD analysis of the Hi–C maps. The average insulation score is shown inset into each corresponding panel. C Aggregate loop analysis of the Hi–C maps. The average strength of loops is shown inset into each corresponding panel

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