Fig. 7
From: Differential usage of DNA modifications in neurons, astrocytes, and microglia
Differentially methylated CG regions. Differentially methylated CG regions (DMCGRs) were determined between cell types. Distribution of mCG differences A was plotted, along with overlap of hyper- B and hypo- C DMCGRs between the three comparisons. Genomic distribution and magnitude of DMCGRs for astrocytes vs neurons D, microglia vs neurons E, and astrocytes vs microglia F. Relative over- and under-representation in genic features for astrocytes vs neurons G, microglia vs neurons H, and astrocytes vs microglia I. Top enriched transcription factor binding motifs for astrocytes vs neurons J, microglia vs neurons K, and astrocytes vs microglia L. Genic regions containing no DMCGRs were notated as “n.d.” (Woolf logit method for 95% confidence intervals, Fisher’s exact test for two-sided p-values; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)