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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Estimating genome-wide DNA methylation heterogeneity with methylation patterns

Fig. 4

Comparison between methylation heterogeneity and methylation levels and the evaluation of PWS heterogeneity. A The proportion (left) and the enrichment plot (right) of DHRs at different genomic features. B Venn diagram of DHGs and DMGs. C Methylation heterogeneity heatmap of DHGs in the 3 stages of CRC samples. D IGV illustration of methylation heterogeneity estimated using PWS around CPXM2, with the DHR shaded in orange. Each blue bar indicates the mean methylation heterogeneity in bins of 400 bp, and the exact values of the bars at the DHR are labelled. E Composition of methylation patterns in all samples within a specific CG window 4 within the DHR from D for identifying a potential disease pattern

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