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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Expression analysis suggests that DNMT3L is required for oocyte de novo DNA methylation only in Muridae and Cricetidae rodents

Fig. 2

Dnmt3l oocyte promoter sequence conservation in rodents. a Screenshot of a reverse complement of Aire intron 3 multiple sequence alignment with highlighted conserved promoter sequences in rodents with available sequences in Ensembl genome database. CH Chinchillidae, BA Bathyergidae, SC Sciuridae, CR Cricetidae, MU Muridae, SP Spalacidae, DI Dipodidae, CA Castoridae, X Scandentia. b PhastCons scores across mouse Aire intron 3 in Muridae and Cricetidae (except prairie vole) rodents on the left and all rodents with available sequence in the Ensembl genome database on the right. Regions highlighted in light grey indicate highly conserved regions identified by PhastCons. The presumed TBPL2/TFIIA binding motif is highlighted in yellow and CT-rich and GA-rich regions surrounding the TSS are highlighted in blue

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Epigenetics & Chromatin

ISSN: 1756-8935