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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects

Fig. 1

Decreased expression of DOT1L gene in low-folate human NTDs fetuses. A The mRNA level of DOT1L, USP7, USP22, USP44, RNF20 was detected by Nanostring in the NTDs fetuses (n = 11). B Folate concentration of normal fetuses and NTDs fetuses was shown as box plots. C Pearson’s correlation analysis was used between the expressions of DOT1L genes and folate level. All data are shown in mean ± sd. (n = 11), *p > 0.05

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Epigenetics & Chromatin

ISSN: 1756-8935