Fig. 5
From: Development of super-specific epigenome editing by targeted allele-specific DNA methylation
Compilation of ASM targeted by three different sgRNA, one with the SNP in the PAM region and two with the SNP in the seed region. The graphs show the DNA methylation at each CpG site in the different target regions. The x-axis indicates the CpG site number. “scr-sg” refers to samples treated with scrambled sgRNA, “gene-sg” refers to samples treated with the allele-specific sgRNA. The color of the heading indicates which allele was targeted. Error bars show the SD of three independent biological repeats except for ISG15-Seed2 which was conducted twice