Table 2 Effect of cut-offs threshold in detecting breast cancer in validation cohort
From: Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer
Cut-offs (correlation to Healthy median) | Sensitivity (%) | Specificity (%) |
|---|---|---|
0.82 | 100.0% | 75.0% |
0.80 | 90.9% | 75.0% |
0.76 | 72.7% | 75.0% |
0.72 | 63.6% | 100.0% |