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Table 1 Clinical information of the participants in this study

From: Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer

 

Discover cohort 1

Discovery cohort 2

Validation cohort

n

Breasta(N = 3)

Healthyb(N = 3)

Breast (N = 12)

Healthy (N = 12)

Breast (N = 11)

Healthy (N = 8)

Age, years

Breast (49.3 42–54)

Healthy (47.7, 42–51)

Breast (58.2 45–70)

Healthy (54.5, 41–72)

Breast (51.5, 26–71)

Healthy (48.0, 25–57)

Gender:female

Breast (3, 100%)

Healthy (3, 100%)

Breast (12, 100%)

Healthy (12, 100%)

Breast (12, 100%)

Healthy (8, 100%)

Stages

Breast (Post-sugery D393, 1, 33%;

Post-surgery D726, 1, 33%;

Post-surgery D289, 1, 33%)

Healthy (N.A.)

Breast (I, 3, 25%;

II, 5, 42%;

III, 2, 17%;

IV, 2, 17%)

Healthy (N.A.)

Breast (I, 7, 64%;

II, 3, 27%;

III, 1, 9%)

Healthy (N.A.)

  1. aBreast in this table indicates patients with breast cancer
  2. bHealthy in this table indicates healthy individuals