From: Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer
 | Discover cohort 1 | Discovery cohort 2 | Validation cohort |
---|---|---|---|
n | Breasta(N = 3) Healthyb(N = 3) | Breast (N = 12) Healthy (N = 12) | Breast (N = 11) Healthy (N = 8) |
Age, years | Breast (49.3 42–54) Healthy (47.7, 42–51) | Breast (58.2 45–70) Healthy (54.5, 41–72) | Breast (51.5, 26–71) Healthy (48.0, 25–57) |
Gender:female | Breast (3, 100%) Healthy (3, 100%) | Breast (12, 100%) Healthy (12, 100%) | Breast (12, 100%) Healthy (8, 100%) |
Stages | Breast (Post-sugery D393, 1, 33%; Post-surgery D726, 1, 33%; Post-surgery D289, 1, 33%) Healthy (N.A.) | Breast (I, 3, 25%; II, 5, 42%; III, 2, 17%; IV, 2, 17%) Healthy (N.A.) | Breast (I, 7, 64%; II, 3, 27%; III, 1, 9%) Healthy (N.A.) |