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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer

Fig. 6

Detection of breast cancer using DMRs-dependent cfDNA fragmentation profile. A Input-adjusted short fragments ratio was depicted for hypomethylated genomic windows, individual profile was colored according to their Pearson correlation to the healthy median in each genomic window. B Receiver operator characteristics for breast cancer detection using correlation assessment of DMRs-dependent cfDNA fragmentation profile. AUC = 0.909; 95% CI (0.771–1.000). Healthy, healthy individuals; Breast, patients with breast cancer

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