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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation

Fig. 4

Relationship between chromatin accessibility and m6A-related proteins. A The accessibility of potential target genes of m6A-related proteins compared with the accessibility of all genes. Blue represents potential target genes, green represents random genes with same number as potential target genes and red represents all genes we detected. * represents p-value < 0.05 and ** represents p-value < 0.01. B Genes exhibiting various correlations between m6A level and the expression level of METTL14, RBM15 and ALKBH5 show similar accessibility. * represents p-value < 0.05. C Genes exhibiting various correlations between m6A level and the expression level of YTHDC2 and IGF2BP2 show similar accessibility. D Cumulative curve shows the m6A modification levels of genes displaying different correlations between m6A modification levels and expression levels of YTHDC2 and IGF2BP2. neg/not/pos cor: genes whose m6A level or accessibility are negatively/not/positively correlated with the expression of m6A-related proteins

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