Fig. 1
From: Etiology of super-enhancer reprogramming and activation in cancer
Oncogenic signaling results in transcription factor occupancy at gained SEs in cancer. Metagene plots showing TCF4 occupancy (red, left bottom), a transcription factor activated by Wnt signaling, at SEs gained in CRC over normal colon (left top). Metagenes plots showing ERα occupancy (red, right bottom) at SEs gained in ER+ breast cancer over normal breast (right top). Figure reproduced with permission from Elsevier. Please refer to the original publication (Hnisz et al. [7]) for more details and citation