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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: PARP-dependent and NAT10-independent acetylation of N4-cytidine in RNA appears in UV-damaged chromatin

Fig. 1

Increased levels of ac4C RNAs after UV irradiation are identical in the G1, S, and G2 phases of the cell cycle. The density of ac4C RNA was detected in A non-irradiated HeLa Fucci cells and B UVA-irradiated HeLa Fucci cells, stably expressing RFP-tagged cdt1 (red) in the G1 phase and GFP-tagged geminin (green) in the G2 phase of the cell cycle. The S phase is characterized by RFP-cdt1 and GFP-geminin positivity. Scale bars show 5 µm. C Quantification of the fluorescence intensity of ac4C RNA is shown in panels A and B

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