Fig. 5

Overview of oncogenic pathway alterations in the patient cohort. The oncogenic pathways affected in the AEL patients are shown (A) with the number of affected genes in relation to the total number of genes linked to each pathway. The second plot displays the fraction of patients bearing mutations in a given pathway. B For each pathway, Var∣Decrypt allows visualizing the mutated genes for each patient to easily spot the recurrently mutated genes. Oncogenes and tumor suppressor genes are indicated in blue and red, respectively