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Table 2 a priori GO term enrichment at 7 days and 14 days

From: The role of Dmnt1 during spermatogenesis of the insect Oncopeltus fasciatus

 

Pathway

GO Term

Number of annotated genes

NES

P value

FDR-adjusted P value

7 days

Cell Cycle

GO:0007049

1045

− 3.224

5.34E-11

3.74E-10

 

Gametogenesis

GO:0007276

1275

− 3.026

1.92E-10

6.73E-10

 

Mitotic Cell Cycle

GO:0000278

738

− 2.813

3.47E-08

8.10E-08

 

Meiotic Cell Cycle

GO:0051321

329

− 2.519

2.93E-05

4.11E-05

 

Spermatogenesis

GO:0007283

493

− 2.371

2.25E-05

3.93E-05

 

Apoptotic Process

GO:0006915

426

− 0.973

4.95E-01

5.77E-01

 

Necrotic Cell Death

GO:0070265

21

− 0.634

9.20E-01

9.20E-01

14 days

Cell Cycle

GO:0007049

1031

0.839

1

1

 

Gametogenesis

GO:0007276

732

0.884

1

1

 

Mitotic Cell Cycle

GO:0000278

324

0.846

1

1

 

Meiotic Cell Cycle

GO:0051321

1256

0.872

1

1

 

Spermatogenesis

GO:0007283

486

0.853

1

1

 

Apoptotic Process

GO:0006915

422

0.939

0.938

1

 

Necrotic Cell Death

GO:0070265

20

0.891

0.755

1

  1. This aligns with a general, global response to the loss of Dnmt1 not heavily, preferentially targeting one or a few pathways. NES normalized enrichment score. Statistically significant values are bolded