Table 1 Â a priori candidate genes tested for differences between 7- and 14-day Control and Dnmt1 knockdown treatments
From: The role of Dmnt1 during spermatogenesis of the insect Oncopeltus fasciatus
Gene Name | Gene ID | Pathway | 7 days | 14 days | ||||
|---|---|---|---|---|---|---|---|---|
Standardized expression | Fold change | FDR-corrected P | Standardized expression | Fold change | FDR-corrected P | |||
Dnmt1 | OFAS015351, OFAS018396 | Cytosine methylation | 7.9 | − 0.185 | 1.20E-03 | 6.3 | − 8.72E-01 | 2.20E-16 |
Wnt-like | OFAS019215 | Cell fate and proliferation | NA | NA | NA | NA | NA | NA |
Wnt-like | OFAS025063 | Cell fate and proliferation | 7.1 | 1.25E-06 | 0.994 | 5.5 | 0.142 | 0.621 |
Frizzled-like | OFAS012753 | Cell fate and proliferation | 7.3 | − 4.82E-06 | 0.037 | 5.7 | − 0.302 | 0.226 |
Frizzled-like | OFAS013300 | Cell fate and proliferation | 9.5 | − 7.16E-06 | 0.245 | 7.8 | 0.047 | 0.766 |
Frizzled-like | OFAS013301 | Cell fate and proliferation | 7.8 | 1.03E-06 | 0.955 | 6.3 | − 0.036 | 0.875 |
Vasa | OFAS025106 | Germ cell Development | 10.7 | − 3.68E-06 | 0.663 | 8.6 | − 0.622 | 0.013 |
CYCB3 | OFAS004926 | Cell cycle control | 7.9 | 1.29E-06 | 0.618 | 5.8 | − 0.337 | 0.268 |
CDC20 | OFAS011085 | Cell cycle control | 12.9 | 1.07E-05 | 0.853 | 10.7 | − 0.743 | 7.47E-05 |
CDC25-like | OFAS004022 | Cell cycle control | 9.0 | − 4.22E-05 | 0.336 | 7.0 | − 0.575 | 0.004 |
CDC25-like | OFAS004025 | Cell cycle control | 7.1 | − 5.29E-05 | 0.938 | 5.5 | 0.027 | 0.925 |
CYCD2 | OFAS016512 | Cell cycle control | NA | NA | NA | NA | NA | NA |
CYCD3 | OFAS016513 | Cell cycle control | 6.4 | 2.72E-06 | 0.149 | 5.2 | 0.384 | 0.178 |
SMC3-like | OFAS014329 | Chromosomal Structure Maintenance | 7.9 | 1.43E-05 | 0.111 | 5.9 | − 0.204 | 0.475 |
SMC3-like | OFAS014330 | Chromosomal Structure Maintenance | 6.7 | − 7.77E-05 | 0.971 | 5.1 | − 0.549 | 0.092 |
Boule | OFAS007982 | meiotic G2/M transition | 12.3 | − 1.98E-06 | 0.121 | 10.2 | − 0.573 | 0.013 |
SPO11 | OFAS017698 | Meiotic Recombination | 9.2 | 8.39E-07 | 0.777 | 7.1 | − 0.453 | 0.052 |
MSH5 | OFAS011763 | Meiotic Recombination | 6.5 | 1.18E-05 | 0.319 | 5.2 | 1.916 | 0.001 |
MND1 | OFAS003294 | Meiotic Recombination | 9.6 | − 9.14E-05 | 0.220 | 7.5 | − 0.258 | 0.157 |
HOP2 | OFAS000825 | Meiotic Recombination | 8.3 | 2.24E-05 | 0.032 | 6.7 | 0.346 | 0.088 |