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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

Fig. 2

Effect of VRK1 depletion of epigenetic modifications of H3K27 in the presence or absence of serum in A549 lung adenocarcinoma cells. The field figure is shown in Additional file 3: Fig. S3. A Effect of VRK1 depletion on histone H3K27 methylation in A549 cells. B Effect of VRK1 depletion on histone H3K9 acetylation in A549 cells. The quantification of H3K27 methylation (left) and acetylation (right) from 50 cells is shown below. The immunoblots of the cell extracts from the experiment are shown at the bottom. The lysate was divided in two for loading in gels to determine each of the H3K27 modifications. ***p < 0.001. siCt, siControl; siV-02, siVRK1-02; siV-03, siVRK1-03

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Epigenetics & Chromatin

ISSN: 1756-8935