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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Premature ovarian insufficiency is associated with global alterations in the regulatory landscape and gene expression in balanced X-autosome translocations

Fig. 3

IGV visualization of differential peaks at 17p12 and expression levels of DEGs within this region. IGV tracks: encode GM12878 H3K27ac in orange, and RefSeq genes. a H3K27ac peak in patients (blue) and controls (pink) at the ARHGAP44 gene body. Note that H3K27ac is decreased in patients. b Two H3K27ac peaks in patients (blue) and controls (pink), one at the promoter region and one at the HS3ST3B1 gene body. Note that both peaks are decreased in patients. c Significant expression difference between patients and controls in FPKM levels of ARHGAP44 and HS3ST3B1 genes, respectively

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Epigenetics & Chromatin

ISSN: 1756-8935