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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Partial erosion on under-methylated regions and chromatin reprogramming contribute to oncogene activation in IDH mutant gliomas

Fig. 3

Transcriptional patterns of phUMR and fhUMR related genes. A Volcano plot displays the statistical significance (y axis) and fold change (x axis) of phUMR and fhUMR related genes between IDH mutant glioma and normal brain tissues (blue, down-regulated phUMR/fhUMR related genes; red, up-regulated phUMRs/fhUMRs related genes). B The functional annotation of up-regulated and down-regulated genes within phUMR/fhUMR on promoter. The p-values were adjusted using BH method. C The barplot shows the statistical significance (y axis) of KEGG terms for phUMR and fhUMR genes. The line indicates the adjusted p-value threshold 0.05

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