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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: An optimized approach for multiplexing single-nuclear ATAC-seq using oligonucleotide-conjugated antibodies

Fig. 5

Integration analysis of snATAC-seq and deeply sequenced bulk ATAC-seq highlights a relationship between peak intensity and peak genomic locations. A UMAP shows the mouse nuclei identified in the snATAC-seq analysis. B Peak intensities of overlapping bulk ATAC-seq peaks were plotted according to the numbers of cell clusters in which the peaks were found in the snATAC-seq analysis. C The distribution of peaks over different genomic features detected in all clusters dichotomized by the peak intensities of overlapping bulk ATAC-seq peaks. High-intensity peaks were most prevalent in exonic regions and promoters, while lower-intensity peaks were most common in the gene body and intergenic regions

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Epigenetics & Chromatin

ISSN: 1756-8935