Fig. 3

Scatterplot showing the nuclear fragment alignment status of individual nuclei. A Based on read counts, nuclei are clustered into quadrants that are human-specific (bottom right, blue), mouse-specific (top left, purple), duplicated (top right, red), or low NuHash counts (bottom left, green). The black dotted lines indicate the cutoff for the counts used for NuHash demultiplexing. B Nuclei are colored by the NuHash demultiplexed status according to the ratios of the number of reads aligned to the human or mouse reference genomes