Fig. 3

Analytical relation between methylation entropy S and methylation probability p in an n-CpG segment, under different settings of spatial correlation parameter r. The 21 curves from top to bottom correspond to \(r=0,\,0.05,\,\ldots ,\,0.95,\,1\). For each r setting, S is shown as a function of p. A: \(n=2\), under homogeneous methylation (i.e., \(p_1=p_2=:p\)). B: \(n=4\) under exchangeable correlation (i.e., \(r_{ij}=r,1\le i\ne j\le 4\)) and homogeneous methylation (i.e., \(p_i=p,1\le i\le 4\))