Fig. 3
From: Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization
Interconnected gene network of paternally provided dibutyl-phthalate (DBP) responsive RNA Elements (RE)s. The gene network highlights those relationships corresponding to the full-length RE-containing RNAs (RE-RNAs) CAMTA2, EFCAB6, PSME4, SMARCC1, PHF10, RARA, FBRS and CUL2. Paternally provided RE-RNA is either fivefold or twofold paternally enriched. Key genes are highlighted based on node color. Dark blue node borders indicate fivefold paternal enrichment, while a green border indicates twofold paternal enrichment. Node color and shape are as follows; pink squares: CRREW (Chromatin remodeler cofactor, RNA interactor, Reader, Eraser, and Writer) RNA, blue square: key RNA that is not a CRREW, orange circle: major enriched biological pathways, bright yellow circle: indicate functions related to acetylation/deacetylation, methylation/demethylation and ubiquination/deubiquination: light yellow circle; specific process related to acetylation/deacetylation, methylation/demethylation and ubiquination/deubiquination, light pink circle: protein complexes that include at least one key gene, purple circle; enriched MSigDB geneset, grey circle; gene function not assigned by an MSigDB geneset, blue circle; MGI phenotype