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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi-C, Micro-C, and promoter capture Micro-C

Fig. 1

Comparison of Hi-C and Micro-C data. A Experimental methods of Hi-C and Micro-C. Unlike Hi-C that uses restriction enzyme, Micro-C uses MNase, allowing to fragment chromatin to mono, di-, and tri-nucleosomes. B Chromatin interaction heatmaps of Hi-C and Micro-C data near chr7p14 region. C Venn diagram of TADs identified from Hi-C and Micro-C. D Triangular heatmaps of Hi-C and Micro-C near chr1p32 region. TADs identified from each data are shown at the bottom. E Average chromatin interaction signals at shared loops (loops found in Hi-C and Micro-C) and unique loops are shown. F Triangular heatmaps of Hi-C and Micro-C near chr7p14 region and loops identified from each data are shown at the bottom

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