Fig. 3
From: Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation
Maternal deletion of Smchd1 results in transient biallelic Xist expression in morula. a Schematic representation of the allele-specific Xist RNA FISH. b, c Imaging of female (b) and (c) male wt and \(\textit{Smchd1}^{mat\Delta }\) E2.75 embryos. Maternal (BL6) and paternal (Cast) alleles are indicated by coloured arrows. d, e Percentage and number of cells in E2.75 female (d) and male (e) embryos with maternal, paternal or biallelic Xist expression. f, g Imaging of female (f) and g male wt and \(\textit{Smchd1}^{mat\Delta }\) E3.5 embryos. h, i Percentage and number of cells in E3.5 female (h) and male (i) embryos with maternal, paternal or biallelic Xist expression. Scale bar: \({50}\,{\upmu }\hbox {m}\). Numbers of embryos and cells scored are indicated on the figure