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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Viral histones: pickpocket’s prize or primordial progenitor?

Fig. 4

Maximum Likelihood trees of histone doublets. The trees are unrooted, but drawn as if rooted on archaeal doublets. Archaea (blue); eukaryotes (orange); Marseilleviridae (green); insect iridoviruses (red). Alignments were made with EMBL-EBI Muscle software and manually trimmed to remove the N-terminal tails, leaving the histone fold domains, the αN helix and docking domain of H2A, and the αC helix of H2B. The alignments were used to make maximum likelihood trees with IQ Tree [129] and viewed and annotated with Dendroscope 3.0 [130]. Numbers in parentheses are SH-aLRT support (%)/Ultrafast Bootstrap support (%)

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