Fig. 3
From: Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development
Ddx4-chd4−/− mice show profound defects in gametogenesis. A H&E-stained histological sections of wild type and ddx4-chd4−/− testis. Stars mark seminiferous tubules with absent germ cells. Note unchanged number and morphology of Sertoli cells (indicated by green arrows). B Histological sections of wild type and ddx4-chd4−/− testis showing seminiferous tubules immunolabeled with Sox9 (a marker of Sertoli cells) and Tra98 (to mark germ cells). P pachytene cells, Se sertoli cells, Rs rounded spermatids. C H&E-stained histological sections of wild type and ddx4-chd4−/− ovaries. F follicles, CL corpora lutea