Fig. 2
From: Evolutionary adaptation of the Polycomb repressive complex 2
Comparison of PRC2 members that exist in both Drosophila and humans. On the left side, the regions of the Drosophila proteins that are also present in human proteins are colored. On the right side, the identity and conservation of the retained regions are shown. Annotated domains are highlighted. BAM: β-addition motif; SANT: SANT (Swi3, Ada2, N-CoR, and TFIIIB) domain; CXC: cysteine-rich domain; SET: SET (Su(var)3–9, Enhancer-of-zeste and Trithorax) domain; WDB: WD40-repeat binding; ZnB: zinc finger binding helix; C2: C2 domain; Zn: zinc finger; VEFS: VEFS (VRN2-EMF2-FIS2-Su(z)12)-Box; WD: W40 repeat; PHD: plant homology domain; WH: winged-helix domain; JmjN: Jumonji N domain; JmjC: Jumonji C domain; ARID: A–T rich interaction domain; ChromoL: chromo-like domain