Table 2 Embryonic phenotypes of mice treated with ethionine and SAM
Pregnant mice (n) | Embryos (n) | Normal n (%) | Resorption n (%) | Growth retardation n (%) | NTDs n (%) | Other malformation n (%) | |
|---|---|---|---|---|---|---|---|
SAM | 36 | 223 | 207 (93.0) | 6 (2.7) | 10 (4.3) | 0 (0) | 0 (0) |
Ethionine | 38 | 261 | 51 (19.5) | 31 (11.8) | 36 (13.7) | 128 (49.3) | 11a4b (5.7) |
Ethionine + SAM | 37 | 246 | 142 (58.1) | 21 (8.1) | 15 (6.1) | 63 (25.6) | 3a2b (2.1) |