Table 1 Details on bisulfite amplicons screened in the study
| Gene locus | chr |
SNP position ID | PCR primers (5′–3′)a | CpG ID | MethQTL distance (bp) |
MethQTL deltab EPIC, NGS |
|---|---|---|---|---|---|---|
| PON1 | 7 |
94,953,895 rs705379 |
TCTTTCCCTACACGACGCTCTTCCGATCTgattggtggtttttgaagagtgttagtttt GTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTccataatcaaactactaaatctctctaaaac | cg01874867, cg20119798 |
164 249 | + 14.9%, + 39.7% |
| ZNF155 | 19 |
44,488,352 rs62116613 |
TCTTTCCCTACACGACGCTCTTCCGATCTggttgataggttagaatttataggttt GTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTcacatacttaactcaaaccacctt | cg23456212, cg20451226 |
182 171 | + 7.8%, + 13.3% |
| NRG2 | 5 |
139,340,779 rs6580323 |
TCTTTCCCTACACGACGCTCTTCCGATCTtttatgaattttgaagaagttgttaggt GTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTcacatacaaaactaaaacctaaatcc | cg22710094 | 85 | − 5.1%, − 20.1% |