Table 1 Details on bisulfite amplicons screened in the study
Gene locus | chr | SNP position ID | PCR primers (5′–3′)a | CpG ID | MethQTL distance (bp) | MethQTL deltab EPIC, NGS |
|---|---|---|---|---|---|---|
PON1 | 7 | 94,953,895 rs705379 | TCTTTCCCTACACGACGCTCTTCCGATCTgattggtggtttttgaagagtgttagtttt GTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTccataatcaaactactaaatctctctaaaac | cg01874867, cg20119798 | 164 249 | + 14.9%, + 39.7% |
ZNF155 | 19 | 44,488,352 rs62116613 | TCTTTCCCTACACGACGCTCTTCCGATCTggttgataggttagaatttataggttt GTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTcacatacttaactcaaaccacctt | cg23456212, cg20451226 | 182 171 | + 7.8%, + 13.3% |
NRG2 | 5 | 139,340,779 rs6580323 | TCTTTCCCTACACGACGCTCTTCCGATCTtttatgaattttgaagaagttgttaggt GTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTcacatacaaaactaaaacctaaatcc | cg22710094 | 85 | − 5.1%, − 20.1% |