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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Fig. 3

Common and tissue-specific methQTLs identified through colocalization analysis. A To define tissue specificity, we employed MAGAR on the four tissues/cell types independently to obtain methQTL statistics. These were used in pairwise colocalization analyses to define common and tissue-specific methQTL, as well as methQTLs shared across several tissues. B Number of tissue-specific methQTLs per tissue and methQTLs shared across different tissues according to the colocalization analysis. Common methQTLs were shared according to the colocalization analysis and had methQTL P-values below the cutoff in all tissues. C Examples of four common methQTLs located in vicinity to PON1, LGR6, LCE3D, and RIBC2

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Epigenetics & Chromatin

ISSN: 1756-8935